1374030-87-1Relevant academic research and scientific papers
Zn(ii) chloride-catalyzed direct coupling of various alkynes with acetals: Facile and inexpensive access to functionalized propargyl ethers
Suzuki, Itaru,Yasuda, Makoto,Baba, Akio
, p. 11620 - 11622 (2013)
The coupling of acetals with various alkynes was achieved using only 1 mol% of inexpensive and mild Lewis acid ZnCl2, which furnished propargyl ethers. The coupling was catalyzed by Zn(OMe)Cl, which was generated in situ to form an alkynylzinc species. This protocol was allowed to expand to a one-pot subsequent reaction with allylchlorosilane to obtain a 1,4-enyne product.
An alternative approach to direct aldol reaction based on gold-catalyzed methoxyl transfer
Zhang, Moran,Wang, Yunxia,Yang, Yang,Hu, Xiangdong
supporting information; experimental part, p. 981 - 985 (2012/06/30)
A mild and catalyzed alternative to the direct aldol reaction has been developed based on the gold-catalyzed methoxy group transfer from dimethyl acetals to terminal alkynes. Due to the simultaneous activation of the acetals, this aldol approach is only functional for acetals but not aldehydes. A ligand effect from the gold complex has also been observed. Copyright
