1374104-92-3

Upstream product

• 1374036-17-5 (S,1R,1'R,2Z,2'Z)-[1,1'-biphenyl]-4,4'-diylbis(2-oxoethane-2,1-diyl)bis(2-((S)-1-fluoro-2-((methoxycarbonyl)amino)-3-methylbutylidene)cyclopentanecarboxylate)acid 

Downstream Products

• 1374036-09-5 dimethyl ((1Z,1'Z,2S,2'S)-((2R,2'R)-(5,5'-([1,1'-biphenyl]-4,4'-diyl)bis(1H-imidazole-5,2-diyl))bis-(cyclopentan-2-yl-1-ylidene))bis(1-fluoro-3-methylbutan-2-yl-1-ylidene))dicarbamate hydrochloride 

Relevant academic research and scientific papers

Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics

The HCV non-structural protein NS5A has been established as a viable target for the development of direct acting antiviral therapy. From computational modeling studies strong intra-molecular hydrogen bonds were found to be a common structural moiety withi