137411-35-9 Usage
Chemical class
Quinazoline-based molecules
Structure
Contains a triazolo ring fused to a quinazoline ring and a piperazine moiety substituted at the 5th position with a furanyl group and at the 9th position with a chloro group.
Biological activities
Has potential biological activities and may be used in pharmaceutical research for the development of new drugs targeting specific receptors or enzymes.
Function and effects
Exact function and effects are still under investigation, and further research is needed to fully understand its properties and potential applications.
Applications
Potential use in the development of new drugs for various therapeutic areas, including oncology, neurology, and cardiovascular diseases.
Research status
Currently under investigation, with ongoing studies to determine its potential as a therapeutic agent.
Safety and toxicity
Information on safety and toxicity is not provided in the material, and further research is needed to fully understand its safety profile.
Synthesis
The synthesis of 1,2,4-Triazolo[4,3-c]quinazoline,
9-chloro-3-(2-furanyl)-5-(4-phenyl-1-piperazinyl)- is not described in the material, but it is likely to involve the formation of the triazolo and quinazoline rings, as well as the introduction of the furanyl and phenylpiperazine substituents.
Check Digit Verification of cas no
The CAS Registry Mumber 137411-35-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,4,1 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 137411-35:
(8*1)+(7*3)+(6*7)+(5*4)+(4*1)+(3*1)+(2*3)+(1*5)=109
109 % 10 = 9
So 137411-35-9 is a valid CAS Registry Number.
137411-35-9Relevant academic research and scientific papers
AMIDINOYL ISOTHIOCYANATES IN THE SYNTHESIS OF CONDENSED QUINAZOLINES. PREPARATION OF 3-ARYL-5,9-DISTRIBUTED s-TRIAZOLOQUINAZOLINES
Spirkova, Katarina,Stankovsky, Stefan
, p. 1719 - 1724 (2007/10/02)
3-Aryl-5-((4-phenyl)piperazinyl)-9-chloro-s-triazoloquinazolines were prepared by an oxidative cyclization of the corresponding arylhydrazones.The IR and 1H NMR spectra of final products are presented.
