13743-07-2 Usage
Uses
Used in Oncology:
1-(2-Hydroxyethyl)-1-nitrosourea is used as an anticancer agent for the treatment of brain tumors. It is employed for its ability to form DNA interstrand cross-links, thereby inhibiting DNA replication and inducing cell death in cancer cells.
However, its use has been limited due to its high toxicity and potential for causing serious side effects, such as renal and hepatic toxicity, as well as myelosuppression. Additionally, it has been found to have mutagenic and carcinogenic properties, leading to its classification as a potential human carcinogen by the International Agency for Research on Cancer. Despite these limitations, research continues to explore its potential role in cancer treatment with the aim of developing safer and more effective derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 13743-07-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,4 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13743-07:
(7*1)+(6*3)+(5*7)+(4*4)+(3*3)+(2*0)+(1*7)=92
92 % 10 = 2
So 13743-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H7N3O3/c4-3(8)6(5-9)1-2-7/h7H,1-2H2,(H2,4,8)
