1374334-49-2Relevant academic research and scientific papers
RING CONSTRAINED ANALOGS AS ARGINASE INHIBITORS
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, (2013/11/05)
The inventive boronic acid analogs are potent inhibitors of Arginase I and II activity. These compounds are candidate therapeutics for treating a disease or disorder associated with an imbalance in the activity or concentration of cellular arginase I and
BORONATES AS ARGINASE INHIBITORS
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, (2012/05/19)
Compounds according to Formula I are potent inhibitors of Arginase I and II activity: (I) where R1, R2, R3, R4, D, W, X, Y, and Z are defined in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use in treating or preventing a disease or a condition associated with arginase activity.
