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137438-23-4

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137438-23-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 137438-23-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,4,3 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 137438-23:
(8*1)+(7*3)+(6*7)+(5*4)+(4*3)+(3*8)+(2*2)+(1*3)=134
134 % 10 = 4
So 137438-23-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H11ClN2S/c1-6-2-3-7-8(4-6)15-11-9(7)10(12)13-5-14-11/h5-6H,2-4H2,1H3

137438-23-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H33439)  4-Chloro-7-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidine, 96%   

  • 137438-23-4

  • 1g

  • 835.0CNY

  • Detail
  • Alfa Aesar

  • (H33439)  4-Chloro-7-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidine, 96%   

  • 137438-23-4

  • 5g

  • 2783.0CNY

  • Detail

137438-23-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine

1.2 Other means of identification

Product number -
Other names 4-chloro-7-methyl-5,6,7,8-tetrahydrobenzo[b]thiopheno[2,3-d]pyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137438-23-4 SDS

137438-23-4Downstream Products

137438-23-4Relevant articles and documents

Identification of 4-methoxythieno[2,3-d]pyrimidines as FGFR1 inhibitors

Balanda, A. O.,Bdzhola, V. G.,Kotey, I. M.,Pletnova, L. V.,Protopopov, M. V.,Prykhod’ko, A. O.,Starosyla, S. A.,Yarmoluk, S. M.

, p. 152 - 162 (2020/06/02)

Aim. To identify novel FGFR1 inhibitors using virtual screening approach. Methods. We used methods of organic synthesis, molecular docking via the Autodock 4.2.6 program package and in vitro biochemical tests with γ-32P. Results. In vitro experiments showed that 9 of 23 tested compounds possess inhibitory activity against FGFR1 with IC50 values in the range from 0.9 to 5.6 μM. Conclusions. Nine FGFR1 inhibitors were developed. The mode of compounds binding with the ATP-acceptor site was determined using molecular docking methods and the dependence of the compounds’ activity on the substituents R1, R4 and R5 was evaluated.

SUBSTITUTED THIENOPYRIMIDINES AND PHARMACEUTICAL USE THEREOF

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Page/Page column 76; 78, (2014/08/19)

The present invention relates to substituted thienopyrimidine compounds of general formula(I)as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.

Synthesis of 7-methyl-4-substituted-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidi nes as antimicrobial agents

Patil,Sadana

, p. 169 - 171 (2007/10/02)

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