137444-57-6

Basic information

• Product Name: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(3-chloro-2-thienyl)-, (2E)-
• CAS NO: 137444-57-6
• Molecular Formula: C13H8Cl2OS
• Molecular Weight: 283.178
• Mol File: 137444-57-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(3-chloro-2-thienyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(3-chloro-2-thienyl)-, (2E)-(137444-57-6)
• EPA Substance Registry System: 2-Propen-1-one, 3-(4-chlorophenyl)-1-(3-chloro-2-thienyl)-, (2E)-(137444-57-6)

Safety Data

• Hazardous Substances Data: 137444-57-6(Hazardous Substances Data)

Upstream product

• 89581-82-8 2-acetyl-3-chlorothiophene 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 137444-81-6 4-(4-chlorophenyl)-6-(3-chloro-2-thienyl)-2-methoxynicotinonitrile 
• 478489-95-1 5-(4-chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazole 
• 478489-93-9 5-(4-chloro-phenyl)-1-(3-chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-4,5-dihydro-1H-pyrazole 
• 478489-48-4 3-(4-Chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-1H-pyrazole 
• 478489-97-3 5-(4-Chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-1-(4-methane-sulfonyl-phenyl)-4,5-dihydro-pyrazole 
• 478489-96-2 5-(4-chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-1-(4-carboxy-phenyl)-4,5-dihydro-pyrazole 
• 478489-92-8 5-(4-chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-1-methyl-4,5-dihydro-1H-pyrazole 
• 478489-94-0 1,5-bis-(4-chloro-phenyl)-3-(3-chloro-thiophen-2-yl)-4,5-dihydro-1H-pyrazole 

Relevant articles and documents

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.