1374451-45-2Relevant academic research and scientific papers
Rh(III)-Catalyzed Regioselective Acetylation of sp2 C?H Bond Starting from Paraformaldehyde
Wan, Ting,Du, Sidong,Pi, Chao,Wang, Yong,Li, Rongbin,Wu, Yangjie,Cui, Xiuling
, p. 3791 - 3796 (2019)
Rh(III)-catalyzed acetylation of sp2 C?H bonds has been realized using paraformaldehyde as an acetylating reagent. This procedure features simultaneous formation of two C?C bonds, external oxidants free, and water as the sole byproducts, thus offering an environmentally benign acetylation of arenes. A range of functional groups tolerance were observed.
Dual photoredox/palladium-catalyzed C-H acylation of 2-arylpyridines with oxime esters
He, Bin-Qing,Gao, Yuan,Wang, Peng-Zi,Wu, Hong,Zhou, Hong-Bin,Liu, Xiao-Peng,Chen, Jia-Rong
supporting information, p. 373 - 377 (2020/09/11)
An unprecedented dual photoredox/palladium-catalyzed iminyl-radical-mediated C-C bond cleavage and directed ortho C-H acylation of 2-arylpyridines by using oxime esters is described. Oxime esters can serve as efficient acyl sources through formation of the corresponding acyl radicals by photoredox-catalyzed iminyl-radical-mediated C-C bond cleavage. This redox-neutral protocol features excellent regioselectivity, a broad substrate scope, and good functional-group tolerance with respect to both components, giving a broad range of aryl ketones with generally good yields.
Manganese-Catalyzed Direct Nucleophilic C(sp2)-H Addition to Aldehydes and Nitriles
Zhou, Bingwei,Hu, Yuanyuan,Wang, Congyang
supporting information, p. 13659 - 13663 (2015/11/16)
Herein, a manganese-catalyzed nucleophilic addition of inert C(sp2)-H bonds to aldehydes and nitriles is disclosed by virtue of a dual activation strategy. The reactions feature mild reaction conditions, excellent regio- and stereoselectivity, and a wide substrate scope, which includes both aromatic and olefinic C-H bonds, as well as a large variety of aldehydes and nitriles. Moreover, mechanistic studies shed light on possible catalytic cycles.
