1374452-60-4

Basic information

• Product Name: 1-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester
• Synonyms: 1-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester
• CAS NO: 1374452-60-4
• Molecular Weight: 432.879
• Mol File: 1374452-60-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester(1374452-60-4)
• EPA Substance Registry System: 1-[4-(tert-butoxycarbonylamino-methyl)-phenyl]-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester(1374452-60-4)

Safety Data

• Hazardous Substances Data: 1374452-60-4(Hazardous Substances Data)

Upstream product

• 489446-42-6 4-((tert-butoxycarbonylamino)methyl)phenylboronic acid 
• 1374452-59-1 3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester 
• 113162-36-0 4-fluoro-1H-indole-2-carboxylic acid methyl ester 

Downstream Products

• 1374452-58-0 1-(4-aminomethyl-phenyl)-3-chloro-4-fluoro-1H-indole-2-carboxylic acid methyl ester 

Relevant articles and documents

INDOLE DERIVATIVES

The present invention relates to the indole derivatives of formula (I), wherein R1-R6 and X are defined in the claims and optical antipodes or racemates and/or salts thereof which are selective antagonists of bradykinin B1 to process for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.