137452-48-3Relevant academic research and scientific papers
A convenient synthesis of 4-aminomethyl-L-phenylalanine
Hartman,Halczenko
, p. 2103 - 2107 (2007/10/02)
N-Boc-4-aminomethyl-L-phenylalanine is prepared from N-Boc-4-iodophenylalanine in 78% yield over three steps. The method features an efficient Pd-catalyzed carbonylation, oxime formation, and subsequent catalytic reduction employing an ethanol/water/acetic acid solvent system which is crucial to successful reaction.
