1374559-21-3Relevant academic research and scientific papers
Highly efficient asymmetric Michael addition of diaryl phosphine oxides to α,β-unsaturated N-acylated oxazolidin-2-ones
Zhao, Depeng,Wang, Linqing,Yang, Dongxu,Zhang, Yixin,Wang, Rui
, p. 881 - 883 (2012)
A highly efficient asymmetric Michael reaction of diaryl phosphine oxides with α,β-unsaturated N-acylated oxazolidinones has been developed. Excellent enantioselectivities (up to >99 % ee) and chemical yields (up to 99 %) were achieved with a broad substrate scope of the oxazolidinones. The bidentate property of oxazolidinones was found to be critical for high enantioselectivities.
