1374575-83-3Relevant academic research and scientific papers
Propargylation of CoQ0 through the Redox Chain Reaction
Pawlowski, Robert,Stodulski, MacIej,Mlynarski, Jacek
, p. 683 - 692 (2022/01/04)
An efficient catalytic propargylation of CoQ0 is described by employing the cooperative effect of Sc(OTf)3 and Hantzsch ester. It is suggested to work through the redox chain reaction, which involves hydroquinone and dimeric propargylic moiety intermediates. A broad range of propargylic alcohols can be converted into the appropriate derivatives of CoQ0 containing triple bonds in good to excellent yields. The mechanism of the given transformation is also discussed.
Copper-Catalyzed Dehydrative Cyclization of 1-(2-Hydroxyphenyl)propargyl Alcohols with P(O)H Compounds for the Synthesis of 2-Phosphorylmethylbenzofurans
Zhang, Ming,Yang, Jianlin,Xu, Qing,Dong, Chao,Han, Li-Biao,Shen, Ruwei
supporting information, p. 334 - 345 (2018/01/15)
A tetrakis(acetonitrile)copper(I) hexafluorophosphate [Cu(MeCN)PF6]-catalyzed dehydrative reaction of 1-(2-hydroxyphenyl)propargyl alcohols with diarylphosphine oxides has been developed to provide an efficient synthesis of phosphorylated benzo
Directing group assisted nucleophilic substitution of propargylic alcohols via o -quinone methide intermediates: Br??nsted acid catalyzed, highly enantio- and diastereoselective synthesis of 7-alkynyl-12a-acetamido-substituted benzoxanthenes
Saha, Satyajit,Schneider, Christoph
supporting information, p. 648 - 651 (2015/03/05)
BINOL-based, chiral phosphoric acids catalyze the substitution of 1-(o-hydroxyphenyl)propargylic alcohols with enamides to furnish 7-alkynyl-12a-acetamido-substituted benzo[c]xanthenes and related heterocycles in a one-pot operation with excellent diastereo- and enantioselectivity. Ambient reaction temperature, operationally simple reaction conditions, low catalyst loading, high yields, and excellent stereocontrol are attractive features of this process and make it a highly practical and versatile transformation.
Highly efficient activation of organosilanes with η2-aldehyde nickel complexes: Key for catalytic syntheses of aryl-, vinyl-, and alkynyl-benzoxasiloles
Hoshimoto, Yoichi,Yabuki, Hayato,Kumar, Ravindra,Suzuki, Haruka,Ohashi, Masato,Ogoshi, Sensuke
, p. 16752 - 16755 (2015/01/16)
An η2-aldehyde nickel complex was utilized as an effective activator for an organosilane in order to generate a hypervalent silicate reactant for the first time. This method was successfully applied to the highly efficient syntheses of 3-aryl-, vinyl-, and alkynyl-2,1-benzoxasiloles from benzaldehydes with aryl-, vinyl-, and alkynylsilyl groups at the ortho position. Initial mechanistic studies revealed that an intermolecular aryl transfer process was involved in the reaction mechanism. The formation of an η2-aldehyde complex was directly confirmed by NMR.
A new copper(I)-catalyzed cycloetherification/acid-catalyzed allylic nucleophilic substitution for one-pot synthesis of 2-substituted benzofurans
Li, Xin,Xue, Jijun,Chen, Rui,Li, Ying
supporting information; experimental part, p. 1043 - 1046 (2012/06/04)
A new copper(I)-catalyzed cycloetherification followed by an acid-catalyzed allylic nucleophilic substitution have been developed for the one-pot synthesis of 2-substituted benzofurans. This one-pot reaction proceeds efficiently under extremely mild conditions with simple and inexpensive catalysts, providing diversely substituted benzofurans in good to excellent yields. Georg Thieme Verlag Stuttgart. New York.
Copper(I)-catalyzed hydroalkoxylation/hydrogen-bonding-induced asymmetric hetero-diels-alder cycloaddition cascade: An approach to aromatic spiroketals
Li, Xin,Xue, Jijun,Huang, Chusheng,Li, Ying
supporting information; experimental part, p. 903 - 906 (2012/07/03)
One thing leads to another: Bis(benzannelated) 5,6-spiroketal skeletons can be constructed by an efficient cascade process involving an unprecedented CuI-catalyzed intramolecular alkyne hydroalkoxylation and an asymmetric hetero-Diels-Alder cyc
