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TAK-875, also known as fasiglifam, is a chemical compound that functions as a selective GPR40 agonist. It is an investigational drug primarily developed for the treatment of type 2 diabetes. TAK-875 operates by enhancing glucose-stimulated insulin secretion and simultaneously reducing hepatic glucose production, which results in improved glycemic control. Although it has demonstrated superior efficacy and tolerability in clinical trials compared to existing diabetes medications, its development was paused due to concerns regarding potential liver toxicity. Despite these safety concerns, TAK-875 may still have potential as a diabetes treatment if the safety issues can be resolved.

1374598-80-7

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1374598-80-7 Usage

Uses

Used in Pharmaceutical Industry:
TAK-875 is used as an investigational drug for the treatment of type 2 diabetes. It is utilized for its ability to increase insulin secretion in response to glucose and decrease the production of glucose by the liver, thereby improving the overall management of blood sugar levels in patients with type 2 diabetes.
However, due to the concerns about liver toxicity, further research and development are required to ensure the safety and efficacy of TAK-875 before it can be considered for widespread clinical use. If these safety concerns are addressed, TAK-875 may offer a promising alternative or adjunct to existing diabetes medications.

Check Digit Verification of cas no

The CAS Registry Mumber 1374598-80-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,5,9 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1374598-80:
(9*1)+(8*3)+(7*7)+(6*4)+(5*5)+(4*9)+(3*8)+(2*8)+(1*0)=207
207 % 10 = 7
So 1374598-80-7 is a valid CAS Registry Number.

1374598-80-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]acetic acid,hydrate

1.2 Other means of identification

Product number -
Other names (3S)-6-((2',6'-Dimethyl-4'-(3-(methylsulfonyl)propoxy) biphenyl-3-yl)methoxy)-2,3-dihydro-l-benzofuran-3-yl)acetic acid hemihydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1374598-80-7 SDS

1374598-80-7Upstream product

1374598-80-7Downstream Products

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