1374636-85-7

Upstream product

• 1374636-50-6 S-(2-bromo-4-chlorophenyl)benzenesulfonothioate 
• 145383-93-3 3-(triisopropylsilyloxy)propyne 
• 31928-44-6 2-bromo-4-chloroiodobenzene 
• 106-47-8 4-chloro-aniline 
• 873-38-1 4-chloro-2-bromoaniline 
• 14757-71-2 1,2-bis(2-bromo-4-chlorophenyl)disulfane 

Downstream Products

• 1374636-94-8 (2-(2-bromo-5-methoxyphenyl)-5-chlorobenzo[b]thiophen-3-yl)methanol 
• 1374636-91-5 ((2-(2-bromo-5-methoxyphenyl)-5-chlorobenzo[b]thiophen-3-yl)methoxy)triisopropylsilane 

Relevant academic research and scientific papers

Synthesis of functionalized benzo[b]thiophenes by the intramolecular copper-catalyzed carbomagnesiation of alkynyl(aryl)thioethers

Highly functional: A copper(I)-catalyzed intramolecular carbomagnesiation under mild conditions transforms readily available alkynyl(aryl)thioethers into magnesiated benzothiophenes. Subsequent reaction with various electrophiles (acid chlorides, allyl bromides, aryl halides) provides polyfunctional benzo[b]thiophenes (see scheme). Further modification of the cyclization products affords highly diversified benzothiophene derivatives and new heterocyclic scaffolds.