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1374639-79-8

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1374639-79-8 Usage

Description

LEE011 (succinate hydrate) is a cyclin-dependent kinase (CDK) inhibitor, a chemical compound that plays a crucial role in the regulation of cell cycle progression. It is specifically designed to target and inhibit the activity of CDK4 and CDK6 enzymes, which are key regulators in cell cycle control. By blocking these enzymes, LEE011 can effectively slow down the growth and division of cancer cells, making it a promising therapeutic agent for the treatment of advanced or metastatic breast cancer.

Uses

Used in Pharmaceutical Industry:
LEE011 (succinate hydrate) is used as an anticancer agent for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced or metastatic breast cancer. Its mechanism of action involves the specific inhibition of CDK4 and CDK6 enzymes, which are essential for cell cycle progression. By targeting these enzymes, LEE011 can effectively suppress tumor growth and improve patient outcomes.
In addition to its primary use in cancer treatment, LEE011 (succinate hydrate) may also have potential applications in other areas of pharmaceutical research and development. Its ability to regulate cell cycle progression could make it a valuable tool for studying the underlying mechanisms of various diseases and conditions, as well as for developing new therapeutic strategies to combat them. However, further research and clinical trials are needed to fully explore and validate these potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1374639-79-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,6,3 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1374639-79:
(9*1)+(8*3)+(7*7)+(6*4)+(5*6)+(4*3)+(3*9)+(2*7)+(1*9)=198
198 % 10 = 8
So 1374639-79-8 is a valid CAS Registry Number.

1374639-79-8Upstream product

1374639-79-8Downstream Products

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