1374641-91-4

Basic information

• Product Name: 4-chloro-6-(3,4-dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile
• Synonyms: 4-chloro-6-(3,4-dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile
• CAS NO: 1374641-91-4
• Molecular Weight: 307.76
• Mol File: 1374641-91-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-6-(3,4-dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-6-(3,4-dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile(1374641-91-4)
• EPA Substance Registry System: 4-chloro-6-(3,4-dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile(1374641-91-4)

Safety Data

• Hazardous Substances Data: 1374641-91-4(Hazardous Substances Data)

Upstream product

• 322399-31-5 C₁₃H₁₁N₃O₃S 
• 322399-31-5 6-(3,4-dimethoxyphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 1374641-94-7 7-(3,4-dimethoxyphenyl)-3-oxo-5-thioxo-2,3,5,6-tetrahydro imidazo[1,2-c]pyrimidine-8-carbonitrile 
• 1374641-96-9 6-(3,4-dimethoxyphenyl)-4-hydrazinyl-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile 
• 1374641-93-6 4-(8-cyano-7-(3,4-dimethoxyphenyl) tetrazolo[1,5-c]pyrimidin-5-ylamino)benzene sulfonamide 
• 1374642-05-3 7-(3,4-dimethoxyphenyl)-3-oxo-5-thioxo-2,3,5,6-tetrahydro-[1,2,4]triazolo [4,3-c]pyrimidine-8-carbonitrile 
• 1374642-06-4 4-(8-cyano-7-(3,4-dimethoxyphenyl)-3-oxo-2,3-dihydro-[1,2,4]triazolo[4,3-c] pyrimidin-5-ylamino)benzenesulfonamide 
• 1374641-92-5 7-(3,4-dimethoxyphenyl)-5-thioxo-5,6-dihydrotetrazolo[1,5-c]pyrimidine-8-carbo nitrile 

Relevant articles and documents

Synthesis of various fused pyrimidine rings and their pharmacological and antimicrobial evaluation

Various fused pyrimidines, such as furo[2,3-d]pyrimidine, triazolo- [1,5-a]pyrimidine and tetrazolo[1,5-a]pyrimidine, were synthesized in the reactions of thioxopyrimidine-6(1H)-ones with ethyl chloroacetate (under different reaction conditions), thiourea and sodium nitrite. Pyrimidine thiones reacted with POCl3/PCl5 to give the chloro derivatives which reacted with sodium azide and thiourea to give tetrazolo[1,5-c]pyrimidines, and pyrimido pyrimidines. Thioxopyrimidine-6(1H)-ones reacted with benzylamine to give pyrrolo[2,3-d]pyrimidinethiones. Theoretical calculation using MIDO/3, Fukui indices and the heat of formation of some compounds were carried out. The pharmacological and antimicrobial activities of some of the synthesized products were also evaluated.