1374645-89-2Relevant academic research and scientific papers
Development of the first menthane-based chiral bis(π-allylpalladium) catalysis: Asymmetric allylation of imines
Fernandes, Rodney A.,Chaudhari, Dipali A.
experimental part, p. 1945 - 1952 (2012/05/20)
A new ethylidene menthane-based chiral π-allylpalladium complex catalyzes the asymmetric allylation of various imines with allyltributylstannane and 1 equiv. of water to give chiral homoallylamines in good yields and enantioselectivities. The reaction was carried out essentially under neutral conditions and displayed a good transfer of chiral information from the menthane skeleton through the formation of a bis(π-allylpalladium) species. This is the first example of menthane-based chiral bis(π-allylpalladium) catalysis. A menthane-based chiral π-allylpalladium-catalyzed asymmetric allylation of various imines has been developed giving chiral homoallylamines in good yields and enantioselectivities. The reaction displays a good transfer of chiral information from the menthane skeleton through the formation of a bis(π-allylpalladium) complex. Copyright
