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Propargyl-PEG3-t-butyl ester is a versatile chemical compound that features an alkyne group and a t-butyl ester group. This molecule is particularly useful in the field of biochemistry and pharmaceuticals due to its unique reactivity and protective properties. The alkyne group allows for efficient reactions with azide-bearing compounds or biomolecules through copper-catalyzed Click Chemistry, a widely used method for creating stable and selective bonds. Additionally, the t-butyl ester group serves as a protective moiety for the carboxyl group, which can be deprotected under acidic conditions, enabling further functionalization and modification of the molecule.

1374658-84-0

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1374658-84-0 Usage

Uses

Used in Bioconjugation:
Propargyl-PEG3-t-butyl ester is used as a bioconjugation agent for the selective and stable attachment of biomolecules, such as proteins, nucleic acids, and other macromolecules. The alkyne group facilitates the copper-catalyzed Click Chemistry reaction, allowing for the formation of strong and specific bonds with azide-modified biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Propargyl-PEG3-t-butyl ester is used as a component in the development of drug delivery systems. The protective t-butyl ester group can be utilized to mask the carboxyl group of a drug molecule, enhancing its stability and bioavailability during delivery. Upon reaching the target site, the t-butyl ester can be deprotected under acidic conditions, releasing the active drug molecule.
Used in Polymer Science:
Propargyl-PEG3-t-butyl ester is employed as a building block in the synthesis of various polymers and copolymers. The alkyne group can be used to initiate polymerization reactions, while the t-butyl ester group provides a means for controlling the polymer's properties, such as its hydrophilicity, biocompatibility, and degradability.
Used in Chemical Synthesis:
In organic chemistry, Propargyl-PEG3-t-butyl ester serves as a valuable intermediate for the synthesis of a wide range of compounds. The alkyne and t-butyl ester groups can be used in various reaction schemes, allowing for the creation of complex molecular structures with diverse applications in fields such as materials science, pharmaceuticals, and agrochemicals.
Used in Diagnostics:
Propargyl-PEG3-t-butyl ester can be utilized in the development of diagnostic tools, such as imaging agents and biosensors. The alkyne group can be used to attach contrast agents or signaling moieties to biomolecules, enabling the detection and monitoring of biological processes at the molecular level.

Check Digit Verification of cas no

The CAS Registry Mumber 1374658-84-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,6,5 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1374658-84:
(9*1)+(8*3)+(7*7)+(6*4)+(5*6)+(4*5)+(3*8)+(2*8)+(1*4)=200
200 % 10 = 0
So 1374658-84-0 is a valid CAS Registry Number.

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