1374675-75-8

Upstream product

• 109431-87-0 (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate 
• 121-51-7 3-nitrobenzenesulphonyl chloride 

Downstream Products

• 1374675-76-9 (S)-3-(2-Chloro-4-fluoro-phenylsulfanyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1374675-77-0 (S)-3-(2-Chloro-4-fluoro-benzenesulfonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1374675-86-1 (S)-3-(2-Chloro-4-pyrazol-1-yl-benzenesulfonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1374675-88-3 (S)-3-((S)-2-Chloro-4-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-benzenesulfonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1374675-81-6 (S)-3-[2-chloro-4-(2,2,2-trifluoro-ethoxy)-benzenesulfonyl]-pyrrolidin-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PYRROLIDINE DERIVATIVES USED AS CATHEPSIN INHIBITORS

The invention relates to a compound of formula (I), wherein A1 to A4 and R1 to R6 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

NOVEL PYRROLIDINE DERIVATIVES

The invention relates to a compound of formula (I) wherein A1 to A4 and R1 to R6 are defined as in the description and in the claims. The compound of formula (I) can be used, for example, as inhibitors of the cysteine protease cathepsin.