1374693-91-0

Basic information

• Product Name: 3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene
• Synonyms: 3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene
• CAS NO: 1374693-91-0
• Molecular Weight: 321.161
• Mol File: 1374693-91-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene(1374693-91-0)
• EPA Substance Registry System: 3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene(1374693-91-0)

Safety Data

• Hazardous Substances Data: 1374693-91-0(Hazardous Substances Data)

Upstream product

• 29421-73-6 3,5-dibromo-2-methylthiophene 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 198345-82-3 (4-(trifluoromethyl)phenyl)zinc(II) bromide 
• 554-14-3 2-Methylthiophene 
• 154566-69-5 3-bromo-2-methylthiophene-5-boronic acid 

Downstream Products

• 1374693-92-1 2-methyl-3-(perfluorocyclopent-1-en-1-yl)-5-(4-(trifluoromethyl)phenyl)thiophene 
• 1374693-90-9 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(p-trifluoromethylphenyl)-3-thienyl]perfluorocyclopentene 

Relevant articles and documents

A versatile organozinc approach to the synthesis of potential organic functional building blocks: 5-substituted 3-bromo-2-methylthiophene derivatives

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Sensitive Assays by Nucleophile-Induced Rearrangement of Photoactivated Diarylethenes

Upon light-induced isomerization, diarylethenes (DAEs) equipped with reactive aldehyde moieties rearrange selectively in the presence of amines, accompanied by decoloration. In a comprehensive study, the probe structure was optimized with regard to its inherent reactivity in the nucleophile-triggered rearrangement reaction. Detailed structure-reactivity relationships could be derived, in particular with regard to the type of integrated (het)aryl moieties as well as the location of the formyl residue, and the probes' intrinsic reactivity with primary and secondary amines was optimized. Utilizing an ancillary base, the initially formed rearrangement product can engage in a subsequent catalytic cycle, leading to an amplified decoloration process. This additional catalytic pathway allows us to enhance the sensitivity of our method and successfully discriminate between amines and thiols. Moreover, probes that exhibit strong analyte-induced fluorescence modulation have been designed to further decrease the detection limit by using a more sensitive read-out. The optimized DAE probes are promising molecular components for future programmable sensing materials and devices.

Photochromism of asymmetrical diarylethenes with a pyrimidine unit: Synthesis and substituent effects

Abstract Five photochromic diarylethenes with a six-membered pyrimidine moiety were synthesized to investigate the effects of the substituents on their photochromic behaviors, and the structures of four of the diarylethenes were determined by single-cryst