137472-38-9

Upstream product

• 162754-68-9 2-(1-hydroxy-1-methylethyl)-1-methyl-1-phenylsilacyclopentane 
• 3401-28-3 1-chloro-1-phenyl-1-silacyclobutane 
• 162754-73-6 1-(2-methyl-1-propenyl)-1-phenylsilacyclobutane 
• 137472-36-7 1-(1,2-epoxy-2-methylpropyl)-1-phenylsilacyclobutane 

Relevant academic research and scientific papers

Nucleophile-induced ring enlargement of 1-(1-iodoalkyl)silacyclobutane and 1-(1,2-epoxyalkyl)silacyclobutane into silacyclopentane. Application to the synthesis of 1,4-diol, 4-alken-1-ol, and 1,4,5-triol

Two methods for ring enlargement of silacyclobutane into silacyclopentane have been described. (1) Treatment of 1-(1-iodoalkyl)silacyclobutane with t-BuOK or AgOAc provided 2-alkyl-1-silacyclopentanes which were easily converted into 1,4-diols by oxidativ

Base-induced rearrangement of oxiranylsilacylobutane into silacyclopentane. Application to stereoselective synthesis of 4-alken-1-ol and 1,4,5-triol

Treatment of 1-methyl-1-(cis-1,2-epoxyhexyl)-1-silacyclobutane 16a with i-PrOLi provided erythro-1-methyl-1-isopropoxy-2-(2-hydroxypentyl)-1-silacyclopentane 17a which was converted into (Z)-4-nonen-1-ol 18, (E)-4-nonen-1-ol 19, or 1,4,5-nonanetriol 20, r