1374764-31-4Relevant articles and documents
Enantioselective α-tosyloxylation of ketones catalyzed by spirobiindane scaffold-based chiral iodoarenes
Yu, Jun,Cui, Jian,Hou, Xue-Sen,Liu, Shan-Shan,Gao, Wen-Chao,Jiang, Shan,Tian, Jun,Zhang, Chi
, p. 2039 - 2055 (2011)
Enantiomerically pure iodoarene (S)-2 and its derivatives (S)-3 to (S)-18 with a spirobiindane scaffold have been synthesized. The evaluation of these new chiral iodoarenes as catalysts in the enantioselective α-tosyloxylation of ketones was performed using m-CPBA as a stoichiometric oxidant, and the synthetically useful α-tosyloxylated ketones were obtained in up to 58% enantiomeric excess (ee).