1374772-05-0Relevant academic research and scientific papers
A Diels-Alder approach to anthrapyran antibiotics
Foulgoc, Laura,Sissouma, Drissa,Evain, Michel,Collet, Sylvain,Guingant, André
, p. 768 - 772 (2012)
A new entry to the synthesis of anthrapyran antibiotics has been accomplished through the synthesis of a 4H-anthra[1,2-b]pyran-4,7,12-trione model. The key step features a Diels-Alder reaction between a substituted 5-vinyl-3,4-dihydro-2H-pyran and naphthoquinone as the dienophile. The resulting tetracyclic adduct is then processed towards the targeted trione in a few steps. Georg Thieme Verlag Stuttgart · New York.
