1374775-83-3Relevant academic research and scientific papers
Highly Z-selective asymmetric conjugate addition of alkynones with pyrazol-5-ones promoted by N,N′-dioxide-metal complexes
Wang, Zhen,Chen, Zhenling,Bai, Sha,Li, Wei,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information; experimental part, p. 2776 - 2779 (2012/05/05)
Highly selective: The title reaction is achieved with high enantiomeric and geometric control and thermodynamically unstable (Z)-enone derivatives are obtained as the major products (see scheme). The procedure tolerates a wide range of substrates to generate optically active pyrazolones with vinyl-substituted quaternary stereocenters. Copyright
