1374792-74-1

Basic information

• Product Name: meso-D-myo-inositol-5-(didecyl phosphate)
• Synonyms: meso-D-myo-inositol-5-(didecyl phosphate)
• CAS NO: 1374792-74-1
• Molecular Weight: 540.675
• Mol File: 1374792-74-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: meso-D-myo-inositol-5-(didecyl phosphate)(CAS DataBase Reference)
• NIST Chemistry Reference: meso-D-myo-inositol-5-(didecyl phosphate)(1374792-74-1)
• EPA Substance Registry System: meso-D-myo-inositol-5-(didecyl phosphate)(1374792-74-1)

Safety Data

• Hazardous Substances Data: 1374792-74-1(Hazardous Substances Data)

Upstream product

• 1374660-06-6 meso-2,4,6-tri-O-benzyl-1,3-O-methylidene-D-myo-inositol-5-(didecyl phosphate) 
• 1374792-73-0 meso-2,4,6-tri-O-benzyl-D-myo-inositol-5-(didecyl phosphate) 
• 129952-31-4 (+/-)-2,4,6-tri-O-benzyl-1,3-O-methylidene-D-myo-inositol 
• 98510-20-4 myo-Inositol orthoformate 
• 114847-11-9 meso-2,4,6-tri-O-benzyl-D-myo-inositol-1,3,5-O-orthoformate 

Relevant articles and documents

Synthesis and antitumor activity of inositol phosphotriester analogues

Inositol phosphates, as important second messengers of signal transduction, regulate many biological functions. However, cell penetration and phospholipase stability could be two main issues faced by inositol phosphate analogues used as lead compounds for drug discovery. Inositol phosphotriester analogues could be more beneficial to diffuse across plasma membrane. In this paper, we describe the design and synthesis of a series of inositol phosphotriester analogues based on phosphatidylinositol, along with the initial antitumor activity analysis. Several compounds exhibited good cytotoxic activity against human cancer cell lines A549, HepG2, MDA-MB-231 and HeLa, especially compound 33 was cytotoxic against all the four cancer cell lines with good IC50 values.