1374844-32-2Relevant academic research and scientific papers
A NEW ORGANOCATALYTIC SYNTHESIS OF CHIRAL PYRAZOLIDINES AND THEIR ANALOGUES
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Page/Page column 8; 9; 10; 11, (2013/07/05)
Disclosed herein is a highly enantio- (75 to 98%ee)and diastereoselective (99 to 100%de)synthesis of functionalised pyrazolidines via tandem a-amination-Corey Chaykovsky reaction of alpha unsubstituted aldehydes.
Organocatalytic sequential α-amination/Corey-Chaykovsky reaction of aldehydes: A high yield synthesis of 4-hydroxypyrazolidine derivatives
Kumar, B. Senthil,Venkataramasubramanian,Sudalai, Arumugam
supporting information; experimental part, p. 2468 - 2471 (2012/07/03)
A tandem reaction of in situ generated α-amino aldehydes with dimethyloxosulfonium methylide under Corey-Chaykovsky reaction conditions proceeds efficiently to give 4-hydroxypyrazolidine derivatives in high yields with excellent enantio- and diastereosele
