Cas 1374858-53-3,C18H12F2N4O2S

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Check Digit Verification of cas no

The CAS Registry Mumber 1374858-53-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,8,5 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1374858-53:
(9*1)+(8*3)+(7*7)+(6*4)+(5*8)+(4*5)+(3*8)+(2*5)+(1*3)=203
203 % 10 = 3
So 1374858-53-3 is a valid CAS Registry Number.

1374858-53-3Upstream product

1374859-23-0 C₁₈H₁₀F₂N₄O₄S

1374858-53-3Downstream Products

1374858-53-3Relevant academic research and scientific papers

Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation

Banerjee, Abhisek,Yadav, Pravin S.,Bajpai, Malini,Sangana, Ramachandra Rao,Gullapalli, Srinivas,Gudi, Girish S.,Gharat, Laxmikant A.

, p. 3223 - 3228 (2012)

The synthesis and structure-activity relationship studies of isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors are discussed. The pharmacokinetic profile of 10 and 21 with adequate CNS penetration, required for in vivo Parkinson's disease mod

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