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Relevant academic research and scientific papers

Breaking pseudo-symmetry in multiantennary complex N-glycans using lanthanide-binding tags and NMR pseudo-contact shifts

Controlling NMR shifts by lanthanides tagged to a "symmetrical" N-glycan (see picture) reveals individual resonances for the residues of the otherwise identical A and B arms. This method provides a global perspective of conformational features and interac

Lanthanide-assisted NMR evaluation of a dynamic ensemble of oligosaccharide conformations

A novel methodology is presented for evaluating a dynamic ensemble of oligosaccharide conformations by lanthanide-assisted NMR spectroscopy combined with molecular dynamics (MD) simulations. The results obtained using the GM3 trisaccharide demonstrated th