1374995-75-1Relevant academic research and scientific papers
Electronically unfavorable addition of electron-deficient olefins to isochromenylium tetrafluoroborates initiated by C-1 O-glycosylation
Yu, Shu-Yan,Hu, Zhi-Long,Zhang, Hao,Wang, Shaozhong,Yao, Zhu-Jun
, p. 2765 - 2768 (2012)
Electronically unfavorable reactions between isochromenylium tetrafluoroborates and electron-deficient olefins have been studied and achieved by assistance of a phenolic hydroxyl group in the olefin substrates, providing the corresponding 2-oxabicyclo[3.3.1]nonane derivatives diastereoselectively in moderate to satisfactory yields. The new methodology is initiated by an intermolecular C-1 O-glycosylation, and completed with an intramolecular Michael addition and an aldol condensation in cascade fashion.
