1375017-71-2Relevant academic research and scientific papers
Formation of CC-type palladacycles with assistance from an apparently innocent NH(CO) functional group
Lee, Jhen-Yi,Huang, Yao-Huei,Liu, Shu-Ya,Cheng, Shun-Chu,Jhou, Yang-Ming,Lii, Jenn-Huei,Lee, Hon Man
, p. 5632 - 5634 (2012/07/14)
A novel cyclometalation pathway to form CC-type palladacycles is reported. Unlike common donor-assisted cyclometalation, the NH(CO) auxiliary group undergoes a deprotonation step to form a palladalactam intermediate. The coordinating nitrogen atom functions as an intramolecular base promoting selective C-H bond cleavage. Without the NH proton, the ortho-N-phenyl C-H is activated instead.
