1375086-23-9Relevant articles and documents
Design and evaluation of pyrazolopyrimidines as KCNQ channel modulators
Osuma, Augustine T.,Xu, Xiangdong,Wang, Zhi,Van Camp, Jennifer A.,Freiberg, Gail M.
, (2019)
Effective treatments of neuropathic pain have been a focus of many discovery programs. KCNQ (kv7) are voltage gated potassium channel openers that have the potential for the treatment of CNS disorders including neuropathic pain. Clinical studies have sugg
Potassium Channel Modulators
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Page/Page column 25-26, (2012/05/21)
Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein R1, R2, R3, R4, and R5 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.