1375103-48-2Relevant academic research and scientific papers
Probing Carbocatalytic Activity of Carbon Nanodots for the Synthesis of Biologically Active Dihydro/Spiro/Glyco Quinazolinones and Aza-Michael Adducts
Majumdar, Biju,Mandani, Sonam,Bhattacharya, Tamalika,Sarma, Daisy,Sarma, Tridib K.
, p. 2097 - 2106 (2017)
Herein, we report the fluorescent carbon dots as an effective and recyclable carbocatalyst for the generation of carbon-heteroatom bond leading to quinazolinone derivatives and aza-Michael adducts under mild reaction conditions. The results establish this nanoscale form of carbon as an alternative carbocatalyst for important acid catalyzed organic transformations. The mild surface acidity of carbon dots imparted by -COOH functionality could effectively catalyze the formation of synthetically challenging spiro/glycoquinazolinones under the present reaction conditions.
Tandem synthesis of 2,3-dihydroquinazolin-4(1H)-ones on grinding under solvent-free conditions
Ding, Quan-Sheng,Zhang, Ji-Lei,Chen, Jiu-Xi,Liu, Miao-Chang,Ding, Jin-Chang,Wu, Hua-Yue
experimental part, p. 375 - 380 (2012/06/04)
Citric acid promoted synthesis of a mini-library 2,3-dihydroquinazolin- 4(1H)-ones with good to excellent yields is achieved by tandem reaction of anthranilamides (or anthranilhydrazides) with aldehydes on grinding at room temperature under solvent-free conditions. This method has notable advantages in terms of simple workup, short reaction time, cost-effective, and environmentally benign. Copyright
