1375148-78-9

Basic information

• Product Name: (2R,3R)-ethyl 2,3-dihydroxy-4-(4-methoxybenzyloxy)-3-methylbutanoate
• Synonyms: (2R,3R)-ethyl 2,3-dihydroxy-4-(4-methoxybenzyloxy)-3-methylbutanoate
• CAS NO: 1375148-78-9
• Molecular Weight: 298.336
• Mol File: 1375148-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-ethyl 2,3-dihydroxy-4-(4-methoxybenzyloxy)-3-methylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-ethyl 2,3-dihydroxy-4-(4-methoxybenzyloxy)-3-methylbutanoate(1375148-78-9)
• EPA Substance Registry System: (2R,3R)-ethyl 2,3-dihydroxy-4-(4-methoxybenzyloxy)-3-methylbutanoate(1375148-78-9)

Safety Data

• Hazardous Substances Data: 1375148-78-9(Hazardous Substances Data)

Upstream product

• 88986-87-2 1-[(4-methoxybenzyl)oxy]propan-2-one 
• 1375148-72-3 (Z)-ethyl 4-(4-methoxybenzyloxy)-3-methylbut-2-enoate 
• 937184-70-8 2-(4-methoxybenzyloxy)-4-methylquinoline 

Downstream Products

• 1375148-88-1 (2S,3R)-4-(4-methoxybenzyloxy)-3-methylbutane-1,2,3-triol 
• 42933-13-1 (2S,3R)-2-methylbutane-1,2,3,4-tetraol 

Relevant articles and documents

Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins

The mevalonate-independent pathway (MIP) is an interesting avenue for antimicrobial lead discovery. Here, we present a unified enantioselective synthesis of all four stereoisomers of 2-C-methyltetrol. These are useful building blocks of many bioactive natural products, including 2-C-methylerythritol phosphate (MEP) of the MIP biosynthetic pathway.