1375303-24-4

Basic information

• Product Name: 1-(5-broMo-2-(trifluoroMethyl)pyridin-4-yl)-2,2,2-trifluoroethanone
• Synonyms: 1-(5-broMo-2-(trifluoroMethyl)pyridin-4-yl)-2,2,2-trifluoroethanone
• CAS NO: 1375303-24-4
• Molecular Formula: C8H2BrF6NO
• Molecular Weight: 322.0019992
• Mol File: 1375303-24-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 234.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.786±0.06 g/cm3(Predicted)
• PKA: -5.53±0.30(Predicted)
• CAS DataBase Reference: 1-(5-broMo-2-(trifluoroMethyl)pyridin-4-yl)-2,2,2-trifluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-broMo-2-(trifluoroMethyl)pyridin-4-yl)-2,2,2-trifluoroethanone(1375303-24-4)
• EPA Substance Registry System: 1-(5-broMo-2-(trifluoroMethyl)pyridin-4-yl)-2,2,2-trifluoroethanone(1375303-24-4)

Safety Data

• Hazardous Substances Data: 1375303-24-4(Hazardous Substances Data)

Upstream product

• 1375303-18-6 C₈H₄BrF₆NO 
• 944904-60-3 5-bromo-2-(trifluoromethyl)isonicotinaldehyde 

Relevant articles and documents

Highly efficient synthesis of aryl and heteroaryl trifluoromethyl ketones via o-iodobenzoic acid (IBX)

A two-step process for the synthesis of aryl and heteroaryl trifluoromethyl ketones from the corresponding aldehydes is described. Trifluoromethyl alcohols were prepared from aryl and heteroaryl aldehydes in excellent yields using catalytic amount of K2CO3. The trifluoromethyl alcohols were then oxidized conveniently and efficiently by o-iodoxybenzoic acid (IBX) under mild conditions to get the desired functionalized aryl and heteroaryl trifluoromethyl ketones.