1375353-41-5Relevant academic research and scientific papers
Supramolecular polymers as dynamic multicomponent cellular uptake carriers
Petkau-Milroy, Katja,Sonntag, Michael H.,Van Onzen, Arthur H. A. M.,Brunsveld, Luc
, p. 8086 - 8089 (2012)
Supramolecular synthesis represents a flexible approach to the generation of dynamic multicomponent materials with tunable properties. Here, cellular uptake systems based on dynamic supramolecular copolymers have been developed using a combination of differently functionalized discotic molecules. Discotics featuring peripheral amine functionalities that endow the supramolecular polymer with cellular uptake capabilities were readily synthesized. This enabled the uptake of otherwise cell-impermeable discotics via cotransport as a function of supramolecular coassembly. Dynamic multicomponent and multifunctional supramolecular polymers represent a novel and unique platform for modular cellular uptake systems.
