1375414-63-3Relevant academic research and scientific papers
Highly stereoselective metal-free oxyaminations using chiral hypervalent iodine reagents
Farid, Umar,Wirth, Thomas
, p. 3462 - 3465 (2012/06/01)
The ring and I: Hypervalent iodine compounds avoid the issues of toxicity or complicated ligands of many transition-metal-based systems. A highly enantioselective oxyamination of alkenes with N-sulfonyl ureas employing chiral, lactic acid-based hypervalent iodine reagents gives a facile synthesis of enantiomerically pure 2-arylproline derivatives (see scheme) for the first time. Copyright
