1375471-07-0

Basic information

• Product Name: tert-butyl [(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl]carbamate
• Synonyms: tert-butyl [(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl]carbamate
• CAS NO: 1375471-07-0
• Molecular Weight: 440.386
• Mol File: 1375471-07-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl [(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl]carbamate(1375471-07-0)
• EPA Substance Registry System: tert-butyl [(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-3-yl]carbamate(1375471-07-0)

Safety Data

• Hazardous Substances Data: 1375471-07-0(Hazardous Substances Data)

Upstream product

• 54923-31-8 5-bromo-2-hydroxy-6-methylpyridine 
• 1375471-02-5 5-bromo-6-methyl-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1375471-03-6 6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)pyridin-2(1H)-one 
• 54923-31-8 5-bromo-6-methyl-1,2-dihydropyridin-2-one 

Downstream Products

• 1375471-09-2 (3S,5S,6R)-3-amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,5-trifluorophenyl)piperidin-2-one hydrochloride 
• 1401008-12-5 C₂₇H₂₄F₆N₄O₄ 

Relevant articles and documents

Piperidinone carboxamide indane CGRP receptor antagonists

The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS

The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.