137568-30-0

Basic information

• Product Name: (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane
• Synonyms: (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane
• CAS NO: 137568-30-0
• Molecular Formula: C7H10O6
• Molecular Weight: 190.1507
• Mol File: 137568-30-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane(137568-30-0)
• EPA Substance Registry System: (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane(137568-30-0)

Safety Data

• Hazardous Substances Data: 137568-30-0(Hazardous Substances Data)

Usage

General Description

The chemical compound (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane, also known as dimethyl 4,5-bis(methoxycarbonyl)-4,5-dihydro-1,3-dioxole-2,2-dicarboxylate, is a cyclic organic compound with the molecular formula C8H10O6. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. (4S,5S)-4,5-Bis(methoxycarbonyl)-1,3-dioxolane is characterized by its dioxolane ring structure, which provides stability and makes it suitable for use in various chemical reactions. It is often utilized as a reagent in organic synthesis due to its ability to undergo nucleophilic substitution reactions. Additionally, it is considered relatively stable under standard laboratory conditions, making it a convenient choice for chemical synthesis processes.

Upstream product

• 109-87-5 Dimethoxymethane 
• 13171-64-7 Dimethyl D-tartrate 
• 608-68-4 dimethyl L-tartrate 
• 50-00-0 formaldehyd 

Relevant articles and documents

Bio-based poly(hexamethylene terephthalate) copolyesters containing cyclic acetalized tartrate units

A cyclic acetal of dimethyl l-tartrate (dimethyl 2,3-di-O-methylene l-threarate, Thx) was used as comonomer of dimethyl terephthalate (DMT) in the polycondensation with 1,6-hexanediol (HD) in the melt. Random copolyesters PHTxThxy with contents in tartrate units up to 50% were obtained with satisfactory molecular weights (Mw between 20,000 and 50,000) and dispersities slightly above 2, and without apparent discoloration. The copolyesters started to decompose above 300 °C. The Tg of the copolyesters oscillated between +9 and -9 °C with values steadily decreasing with increasing contents in Thx units. All the copolyesters as well as the homopolyester entirely made of tartrate units were semicrystalline with Tm falling from ～145 °C for PHT to ～70 °C for PHThx with intermediate values decreasing as the content in Thx increased. Copolyesters containing up to 30% of tartrate units were able to crystallize from the melt at crystallization rates that were delayed by the presence of tartrate units. The PHT70Thx30 copolyester displayed significant hydrodegradability when incubated in aqueous buffer and also certain biodegradability when subjected to the action of porcine pancreas lipases.

Catalytic enantioselective dibromination of allylic alcohols

A new dibromination reaction involving the combination of dibromomalonate as the bromonium source and a titanium bromide species as the bromide source has been developed. Enantioselective catalysis has been achieved through apparent ligand acceleration by a tartaric acid-derived diol.