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Ethanone, 1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]-, commonly known as diphenylcyclopropenone (DPCP), is a chemical compound characterized by its unique structure that features a cyclopropenone ring fused with a methylphenyl and two phenyl groups. Ethanone, 1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]is primarily recognized for its application in dermatological treatments, specifically for the management of alopecia areata, an autoimmune disorder leading to hair loss.
Used in Pharmaceutical Industry:
Ethanone, 1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]is used as a therapeutic agent for the treatment of alopecia areata. It functions by inducing an immune response in the skin, which can potentially reverse the hair loss associated with this condition. Ethanone, 1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]is typically applied topically to the affected areas of the scalp in the form of a solution or ointment, necessitating a series of applications over an extended period to achieve the desired therapeutic effect.
Used in Dermatological Applications:
In the field of dermatology, Ethanone, 1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]is utilized as a hair regrowth stimulant. It is particularly effective for individuals suffering from alopecia areata, where the immune system mistakenly attacks hair follicles. The application of DPCP aims to counteract this autoimmune response and promote the restoration of hair growth.

137570-33-3

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137570-33-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 137570-33-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,5,7 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 137570-33:
(8*1)+(7*3)+(6*7)+(5*5)+(4*7)+(3*0)+(2*3)+(1*3)=133
133 % 10 = 3
So 137570-33-3 is a valid CAS Registry Number.

137570-33-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[1-(4-methylphenyl)-2,3-diphenylcycloprop-2-en-1-yl]ethanone

1.2 Other means of identification

Product number -
Other names Ethanone,1-[1-(4-methylphenyl)-2,3-diphenyl-2-cyclopropen-1-yl]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:137570-33-3 SDS

137570-33-3Relevant academic research and scientific papers

Triplet photochemistry of acyl and imino cyclopropenes. a rearrangement to afford furans and pyrroles: Reaction and mechanism

Zimmerman, Howard E.,Wright, Charles W.

, p. 6603 - 6612 (2007/10/02)

Syntheses of 3-substituted 3-acylcyclopropenes and 3-benzoylcyclopropene imines were devised. A triplet rearrangement of acylcyclopropenes having C-3 aryl substitution to afford furans has been uncovered and studied with several examples. Unlike the singl

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