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(2'R,3S,4'R,5'R)-N-benzyl-1'-((1R)-2-hydroxy-1,2-diphenylethyl)-2'-neopentyl-2-oxo-4'-phenylspiro[indoline-3,3'-pyrrolidine]-5'-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1375747-84-4

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1375747-84-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1375747-84-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,5,7,4 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1375747-84:
(9*1)+(8*3)+(7*7)+(6*5)+(5*7)+(4*4)+(3*7)+(2*8)+(1*4)=204
204 % 10 = 4
So 1375747-84-4 is a valid CAS Registry Number.

1375747-84-4Downstream Products

1375747-84-4Relevant academic research and scientific papers

Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors

Zhao, Yujun,Liu, Liu,Sun, Wei,Lu, Jianfeng,McEachern, Donna,Li, Xiaoqin,Yu, Shanghai,Bernard, Denzil,Ochsenbein, Philippe,Ferey, Vincent,Carry, Jean-Christophe,Deschamps, Jeffrey R.,Sun, Duxin,Wang, Shaomeng

supporting information, p. 7223 - 7234 (2013/06/27)

Small-molecule inhibitors that block the MDM2-p53 protein-protein interaction (MDM2 inhibitors) are being intensely pursued as a new therapeutic strategy for cancer treatment. We previously published a series of spirooxindole-containing compounds as a new

SPIRO-OXINDOLE MDM2 ANTAGONISTS

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Page/Page column 104-105, (2012/05/21)

Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as

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