Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1375800-37-5

Post Buying Request

1375800-37-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1375800-37-5 Usage

General Description

(E)-3-(2-fluorophenyl)-2-Methylacrylaldehyde is a chemical compound with the molecular formula C10H9FO. It is a yellow liquid at room temperature and is commonly used in organic synthesis and chemical research. (E)-3-(2-fluorophenyl)-2-Methylacrylaldehyde is an aldehyde, which means it contains a carbonyl group attached to a hydrogen atom, and it also contains a double bond in its carbon-carbon chain. (E)-3-(2-fluorophenyl)-2-Methylacrylaldehyde is known to have potential biological activities and is used in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical compounds. It is also used in the production of fragrances and flavorings. Additionally, this compound may have potential applications in the development of new materials and as a reagent in organic chemistry reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 1375800-37-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,5,8,0 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1375800-37:
(9*1)+(8*3)+(7*7)+(6*5)+(5*8)+(4*0)+(3*0)+(2*3)+(1*7)=165
165 % 10 = 5
So 1375800-37-5 is a valid CAS Registry Number.

1375800-37-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-3-(2-fluorophenyl)-2-methylacrylaldehyde

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1375800-37-5 SDS

1375800-37-5Relevant articles and documents

Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co–Catalyzed, Enantioselective Proton-Transfer

Metternich, Jan B.,Reiterer, Martin,Jacobsen, Eric N.

, p. 4092 - 4097 (2020/09/01)

We report an enantioselective Nazarov cyclization catalyzed by chiral hydrogen-bond-donors in concert with silyl Lewis acids. The developed transformation provides access to tri-substituted cyclopentenones in high levels of enantioselectivity (up to 95% e.e.) from a variety of simple unactivated dienones. Kinetic and mechanistic studies are consistent with a reversible 4π-electrocyclization C?C bond-forming step followed by rate- and enantio-determining proton-transfer as the mode of catalysis. (Figure presented.).

Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists

Wijtmans, Maikel,Maussang, David,Sirci, Francesco,Scholten, Danny J.,Canals, Meritxell,Muji?-Deli?, Azra,Chong, Milagros,Chatalic, Kristell L.S.,Custers, Hans,Janssen, Elwin,De Graaf, Chris,Smit, Martine J.,De Esch, Iwan J.P.,Leurs, Rob

supporting information; experimental part, p. 184 - 192 (2012/07/14)

The chemokine receptor CXCR7 is an atypical G protein-coupled receptor as it preferentially signals through the β-arrestin pathway rather than through G proteins. CXCR7 is thought to be of importance in cancer and the development of CXCR7-targeting ligands is of huge importance to further elucidate the pharmacology and the therapeutic potential of CXCR7. In the present study, we synthesized 24 derivatives based on a compound scaffold patented by Chemocentryx and obtained CXCR7 ligands with pKi values ranging from 5.3 to 8.1. SAR studies were supported by computational 3D Fingerprint studies, revealing several important affinity descriptors. Two key compounds (29 and 30, VUF11207 and VUF11403) were found to be high-potency ligands that induce recruitment of β-arrestin2 and subsequent internalization of CXCR7, making them important tool compounds in future CXCR7 research.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1375800-37-5