137627-20-4

Upstream product

• 137627-17-9 1-(tert-butyldimethylsilyl)-3-<(trimethylsilyl)oxy>-2-azetidinone 
• 137627-15-7 Toluene-4-sulfonic acid (E)-(R)-5-methylsulfanyl-hex-3-enyl ester 
• 137627-12-4 Thioacetic acid S-[(E)-(R)-1-methyl-5-(tetrahydro-pyran-2-yloxy)-pent-2-enyl] ester 
• 137627-13-5 2-((E)-(R)-5-Methylsulfanyl-hex-3-enyloxy)-tetrahydro-pyran 
• 137694-50-9 (5S,3E)-1-<(tetrahydro-2H-pyran-2-yl)oxy>hex-3-en-5-ol 
• 137627-11-3 (5S,3E)-5-<(tert-butyldimethylsilyl)oxy>hex-3-en-1-ol 
• 137627-16-8 (5R,3E)-1-iodo-5-(methylthio)hex-3-ene 
• 501-53-1 benzyl chloroformate 
• 137627-18-0 (3RS,3'E,5'R)-1-(tert-butyldimethylsilyl)-3-<5'-(methylthio)hex-3'-enyl>-3-<(trimethylsilyl)oxy>-2-oxoazetidine 

Downstream Products

• 137627-23-7 (S)-2-Benzyloxycarbonylamino-4-((S)-3-hydroxy-2-oxo-azetidin-3-yl)-butyric acid 
• 137627-24-8 (S)-2-Benzyloxycarbonylamino-4-((R)-3-hydroxy-2-oxo-azetidin-3-yl)-butyric acid 
• 137627-22-6 (3S,3'S)-3-<3'-<(benzyloxycarbonyl)amino>-3'-carboxypropyl>-3-hydroxy-2-oxoazetidine δ-lactone 
• 137694-52-1 (3R,3'S)-3-<3'-<(benzyloxycarbonyl)amino>-3'-carboxypropyl>-3-hydroxy-2-oxoazetidine δ-lactone 
• 65709-93-5 (3S,3'S)-3-(3'-amino-3'-carboxypropyl)-3-hydroxy-2-azetidinone 
• 137694-51-0 (3R,3'S)-1-(tert-butyldimethylsilyl)-3-<3'-<(benzyloxycarbonyl)amino>-3'-carboxypropyl>-3-hydroxy-2-oxoazetidine δ-lactone 
• 137627-21-5 (3S,3'S)-1-(tert-butyldimethylsilyl)-3-<3'-<(benzyloxycarbonyl)amino>-3'-carboxypropyl>-3-hydroxy-2-oxoazetidine δ-lactone 

Relevant academic research and scientific papers

Enantiospecific Synthesis of (-)-Tabtoxinine &β-Lactam

A convergent, 10-step synthesis of optically active tabtoxinine β-lactam has been described.Key features of the synthetic route include (1) preparation of a new γ-cation amino acid synthon, (-)-4, and its use as an electrophile (3 -> 11); (2) the one-pot conversion of methyl sulfide 11 to the Cbz-protected amine 12 via stereoselective sulfilimine rearrangement; and (3) chemoselective lactone ring opening in spiro lactam 15a.Synthons (-)-4 and 3 are available on a semipreparative scale.