1376298-89-3Relevant academic research and scientific papers
Design and synthesis of new 1,3-benzdiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors
Zarghi, Afshin,Zebardast, Tannaz,Hajighasemali, Fatemeh,Alipoor, Eskandar,Daraie, Bahram,Hedayati, Mehdi
, p. 257 - 264 (2012)
A new group of regioisomeric 2,3-diaryl-1,3-benzdiazinan-4-ones, possessing a methyl sulfonyl pharmacophore, were synthesized and their biological activities were tested for cyclooxygenase-2 (COX-2) inhibitory activity. In vitro COX-1/COX-2 inhibition stu
