137634-83-4

Basic information

• Product Name: 2-benzyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid ethyl ester
• Synonyms: 2-benzyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid ethyl ester
• CAS NO: 137634-83-4
• Molecular Weight: 286.374
• Mol File: 137634-83-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-benzyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid ethyl ester(137634-83-4)
• EPA Substance Registry System: 2-benzyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carboxylic acid ethyl ester(137634-83-4)

Safety Data

• Hazardous Substances Data: 137634-83-4(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 25219-53-8 pyrrolidin-2-ylideneacetic acid ethyl ester 
• 100-46-9 benzylamine 

Relevant articles and documents

Mannich condensations of activated cyclic enamines

The synthesis of Mannich compounds starting from activated enamines, i.e., 2-nitromethylene-pyrrolidine and pyrrolidin-2-ylidene-acetic acid ethyl ester, with various amines and formaldehyde or ethyl glyoxylate are described. In order to furnish new Mannich type molecules and to improve the yields sequential reaction routes and 1,2,3-benzotriazole-substituted adducts as reactants were also tested. Additionally, the steric structure of a tricyclic spiro compound formed unexpectedly in high yield was elucidated in details by modern NMR methods.