1376459-36-7Relevant academic research and scientific papers
Synthesis of acridines and persubstituted phenols from cyclobutenones and active methylene ketones
Han, Xiao-Dan,Zhao, Yu-Long,Meng, Jia,Ren, Chuan-Qing,Liu, Qun
, p. 5173 - 5178 (2012)
A new benzannulation strategy that proceeds via a regiospecific [4 + 2] cycloaddition of readily available cyclobutenones and active methylene ketones has been developed. On the basis of this strategy, persubstituted phenols/anilines with up to six different functional groups on the benzene ring were synthesized in a single step. In addition, a series of acridine derivatives were prepared in excellent yield from persubstituted phenols/anilines.
