1376656-10-8

Basic information

• Product Name: 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-methyl-1-p-tolyl-1H-1,2,3-triazole
• Synonyms: 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-methyl-1-p-tolyl-1H-1,2,3-triazole
• CAS NO: 1376656-10-8
• Molecular Weight: 335.384
• Mol File: 1376656-10-8.mol

Chemical Properties

• CAS DataBase Reference: 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-methyl-1-p-tolyl-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-methyl-1-p-tolyl-1H-1,2,3-triazole(1376656-10-8)
• EPA Substance Registry System: 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-5-methyl-1-p-tolyl-1H-1,2,3-triazole(1376656-10-8)

Safety Data

• Hazardous Substances Data: 1376656-10-8(Hazardous Substances Data)

Upstream product

• 1376656-02-8 (E)-3-(4-fluorophenyl)-1-(5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)prop-2-en-1-one 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 1376656-18-6 5-(4-fluorophenyl)-3-(5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)-N-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide 

Relevant articles and documents

Design and synthesis of new 4-pyrazolin-3-yl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolin-1-ylthiazoles as potential antimicrobial agents

New pyrazolyl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolylthiazoles were synthesized through multi step reactions using 1-tolylyl-4-acetyl-5-methyl- 1,2,3-triazole as a precursor. All the newly synthesized compounds were characterized by spectral and elemental analyses. The structure of 11b was evidenced by X-ray crystallographic study. The newly synthesized compounds were evaluated for their antimicrobial activities and also their minimum inhibitory concentration (MIC) against most of test organisms was performed. Amongst the tested compounds 5a, 5c, 11b and 11c displayed excellent antimicrobial activity.