1376677-06-3Relevant academic research and scientific papers
Three-component synthesis of substituted β-(trifluoromethyl)pyrroles via Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonylic compounds and ammonia or primary amines
Korotaev, Vladislav Yu.,Barkov, Alexey Yu.,Kotovich, Ivan V.,Sosnovskikh, Vyacheslav Ya.
experimental part, p. 42 - 47 (2012/06/29)
A variety of substituted β-(trifluoromethyl)pyrroles were easily synthesized in good yields by a one-pot, three-component Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonyls (ethyl acetoacetate, acetylacetone, benzoylacetone) and amm
