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1-(2-Chloroethyl)-3-benzyl-3-(methylcarbamoyl)triazene, also known as FMCT, is a chemical compound that belongs to the triazene class. It is used as a prodrug in cancer treatment, which is converted into the active metabolite MTIC (3-methyl-(triazen-1-yl)imidazole-4-carboxamide) in the body. MTIC is known for its alkylating properties, which lead to DNA alkylation, cell death, and inhibition of cancer cell growth.

137668-39-4

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137668-39-4 Usage

Uses

Used in Cancer Treatment:
1-(2-Chloroethyl)-3-benzyl-3-(methylcarbamoyl)triazene is used as an alkylating agent for the treatment of various types of cancer, including solid tumors and brain tumors. Its active metabolite, MTIC, alkylates DNA, causing cell death and inhibiting cancer cell growth. FMCT has shown potential in clinical trials, but its use is associated with potential side effects such as myelosuppression, nausea, and vomiting. Further research is needed to fully understand its safety and efficacy profiles.
Used in Pharmaceutical Research:
1-(2-Chloroethyl)-3-benzyl-3-(methylcarbamoyl)triazene is used as a prodrug in the development of new cancer treatments. Its conversion to the active metabolite MTIC provides a promising avenue for the design of novel therapeutic strategies against cancer. 1-(2-Chloroethyl)-3-benzyl-3-(methylcarbamoyl)triazene's mechanism of action and potential for combination therapies are areas of ongoing research in the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 137668-39-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,6,6 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 137668-39:
(8*1)+(7*3)+(6*7)+(5*6)+(4*6)+(3*8)+(2*3)+(1*9)=164
164 % 10 = 4
So 137668-39-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H15ClN4O/c1-13-11(17)16(15-14-8-7-12)9-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3,(H,13,17)/b15-14+

137668-39-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-benzyl-1-(2-chloroethyldiazenyl)-3-methylurea

1.2 Other means of identification

Product number -
Other names Cbzm-1,3,3

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:137668-39-4 SDS

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