137668-75-8

Upstream product

• 914104-08-8 benzyl {2-[4-(hydroxymethyl)phenyl]ethyl}carbamate 
• 501-53-1 benzyl chloroformate 
• 64353-30-6 4-(2-aminoethyl)-benzyl alcohol 

Downstream Products

• 137668-71-4 4-(2-{4-[Hydroxy-(1-methyl-cyclohexyloxy)-phosphorylmethyl]-phenyl}-ethylcarbamoyl)-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 137668-73-6 [4-(2-Amino-ethyl)-benzyl]-phosphonic acid mono-(1-methyl-cyclohexyl) ester 
• 914104-09-9 tert-butyl 4-[4-(2-{[(benzyloxy)carbonyl]amino}ethyl)benzyl]-3-oxopiperazine-1-carboxylate 

Relevant academic research and scientific papers

THIENOPYRIMIDONE COMPOUND

The present invention relates to a compound represented by the formula: wherein Ar is an optionally substituted ring; A is a spacer having a main chain of 1 to 4 atoms; B is a bond, a C1-10 alkylene group or an oxygen atom; R3 and R5 are each independently a hydrogen atom or a substituent; R4 is an optionally substituted cyclic group or an optionally substituted C1-10 alkyl group; and R1 and R2 are each independently a hydrogen atom or a substituent, or R1 and R2 or R1 and B are bonded to form an optionally substituted nitrogen-containing heterocycle, or R1 and Ar are bonded to form an optionally substituted nitrogen-containing fused heterocycle, or a salt thereof. The thienopyrimidone compound of the present invention has a superior melanin-concentrating hormone receptor antagonistic action, and is useful as an agent for the prophylaxis or treatment of obesity and the like.