137675-20-8

Upstream product

• 5779-72-6 2,4,5-trimethylbenzaldehyde 
• 60368-00-5 2,4,5-trimethylbenzaldoxime 
• 137675-09-3 C₁₀H₁₂ClNO 

Downstream Products

• 137675-19-5 5-Phenyl-3-(2,4,5-trimethyl-phenyl)-4,5-dihydro-isoxazole 

Relevant academic research and scientific papers

Palladium-Catalyzed (3+3) Annulation of Allenylethylene Carbonates with Nitrile Oxides

In this paper, we designed and synthesized a new type of cyclic carbonates, allenylethylene carbonates (AECs). With AECs as reactive precursors, we developed palladium-catalyzed (3+3) annulation of AECs with nitrile oxides. Various AECs worked well in this reaction under mild reaction conditions. A variety of 5,6-dihydro-1,4,2-dioxazine derivatives with allenyl quaternary stereocenters can be accessed in a facile manner in high yields (≤98%).